As far as I know, truffles and chantrelle mushrooms aren’t cultivated, and only found in natural settings. But the OP asked about a magical acre that could grow anything, and I was trying to think of something beyond the obvious. That’s why I suggested someone figure out a hypothetical yield for just the fungus. Which suggests another dimension to the problem…
Does the length of time to maturity of the crop factor into this? Considering the price of hardwood lumber, an acre of cherry or oak trees (or probably some more exotic wood) would fetch a pretty hefty sum. But you could have dozens of strawberry harvests in the time it took grow mature trees.
Tomatoes and tobacco are closely related. So are potatoes. You can graft a tomato top onto potato roots and get two crops in the same space. It’s possible you could also graft tomatoes and tobacco onto the same stock. I’ve never heard of anyone trying it.