Ginger Meggs.
A comic strip created in 1921 by Sydney cartoonist Jimmy Bancks who produced the strip until his death in 1952. The baton was taken up by another 4 cartoonists in turn chalking up 102 years in print until discontinued in 2023. Ginger Meggs didn’t age through the series.
Marvin the Android from Hitchhikers Guide.
When Ford, Arthur, Trillian and Zaphod go to Milliways, constructed on the ruins of Magrathea (and therefore the closest restaurant) they find Marvin has been waiting patiently for their return for 576,000,003,579 years.
I’m not familiar with the author or character, but if @Shalmanese is right, it would. Assuming no one wants to correct or contradict the claim, congrats, @Shalmanese, for finding it.
We’re not talking about the in-universe lifespan of a character, but the length of time between the character’s first and last appearances in print, as written by the original author.
Also, this thread excludes comic strips, although a similar thread about comic book characters would no doubt be interesting.
Probably credit should go to Scylla to finding it in 2015. I was merely curious if his prediction came true so I looked up on the Wikipedia and updated the info. I don’t actually know anything about the author or the character except what’s in Wikipedia.