Imagine what a different show it would have been if it had been called:
Sarscape
St. Elsewhere.
And let’s not forget Supertrain!
Wait! Manimal doesn’t start with an “s”! Point proven wrong.
Saved by the Bell
Except that it’s
Smanimal.
And don’t forget
Shill Street Blues
Smaude
Slogan’s Run
The Souter Limits
Slost in Space
Shappy Days
Space Ghost!
What about the show I watch more than all others combined?
Sportscenter!
Don’t forget The State!
Sr. Who - A British sci-fi series about a time/space traveling Mexican.
Sing of the Hill - A animated comedy about a group of thesbians living in rural America.
The Saily Show - A comedy news program devoted to all things nautical.
Saxi - To pay his bills, a jazz musician get a job as a taxi driver.
SHiPs - Hilarious hygencs ensue when motorcycle police officers are reassigned to a coast guard boat.
Sight Court - Justice really is blind in this courtroom when a vision-impaired comedian becomes a judge.
I’ll be darned, it’s true. 
The Sick Van Dyke Show—drama about a lesbian hospital’s ambulance driver.
Sopular—teen drama in a flood-prone high school.
S’reen Acres—Wealthy New Yorker buys a rural mental hospital.
Suturama—TLC’s new plastic surgery show.
And how about the biggest show of the year, every year
Super bowl
Slack Adder—Nature show about aging reptiles
Satman—Life and loves of a chair salesman
Sob—Life and loves of a depressive
The Sold and the Beautiful—Hollywood’s zaniest whore house!
Sheers—“Where everybody cuts your hair”
SAG—Sex and the City, 20 years later
Sexter’s Laboratory—The little perv grows up
Sonny & Marie—The hell with Cher and Donny!
Sappy Days—Pretty much unchanged.
Suckman—Ummm, fill in the blanks yourself . . .
Slipper—They call him Slipper! Slipper! He’s a size seven . . .
Sod the Devil and Bob—Highly unsuccessful cartoon series.
Some Improvement—Not much, but . . .
Sow to Marry a Millionaire—aka The Anna Nicole Show
Six O’clock News
S.R. - the tense medical show about the slow paced action of hours long surgery
Saw and Order - carpentry dealing with the on demand customer.
Don’t forget its followup Saw and Order: Special Victims Unit - when carpentry goes horribly wrong
And all the great philosopher’s names started with “S”, too. (subtle Monty Python reference)
Sirefly - the Independents were vampires who fought in the war. Mal is one of the last vampires.
The Sack Benny Show—“Benny, you’re fired!” “Again?”
The Sickey Mouse Club—“No, not on the rug!”
The Seal World—MTV meets Jacques Cousteau
Sales from the Crypt—“Half off! HAahahahaha!”
The Sod Squad—renamed Queer Eye for the Straight Guy