# Why do my eyedrops taste so bad?

**URL:** <https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891>\
**Category:** Factual Questions\
**Created:** [November 29, 2014, 12:28pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891 "2014-11-29T12:28:33Z")\
**Posts on this page:** 8\
**Page:** 1

<div class="post-metadata">

**Author:** ![Quartz](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/quartz/32/267_2.png) [@Quartz](https://boards.straightdope.com/u/Quartz)\
**Post date:** [November 29, 2014, 12:28pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/1 "2014-11-29T12:28:33Z")

</div>

I’ve been prescribed some eyedrops (prednisolone acetate 1%) and boy do they taste bad. I was surprised to learn that I could taste them in the first place, but in researching that I learned of the lacrimal punctum. But the question remains: **why** do they taste so bad? Which receptors are they activating? Is it something deliberately added to prevent steroid abuse?

Note: I’m under medical care and am NOT looking for medical advice, just an answer to the taste issue.

---

<div class="post-metadata">

**Author:** ![Joey\_P](https://avatars.discourse-cdn.com/v4/letter/j/919ad9/32.png) [@Joey\_P](https://boards.straightdope.com/u/Joey_P)\
**Post date:** [November 29, 2014, 1:04pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/2 "2014-11-29T13:04:16Z")

</div>

It’s probably something in the solution that tastes bad. Also, prednisolone isn’t a muscle building steroid, it’s more along the lines of cortisone, it knocks down swelling. You could probably drink the whole bottle and not have it do much more than get rid of a headache. There’s no abuse potential here.

---

<div class="post-metadata">

**Author:** ![njtt](https://avatars.discourse-cdn.com/v4/letter/n/ecd19e/32.png) [@njtt](https://boards.straightdope.com/u/njtt)\
**Post date:** [November 29, 2014, 2:02pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/3 "2014-11-29T14:02:12Z")

</div>

Lots of medicines - heck, probably most medicines - taste bad. This is usually because they activate the taste buds sensitive to bitter flavors, which are there in the mouth mainly to stop us eating poisons, such as plant alkaloids. Many, perhaps most, medicines are poisons (indeed, not a few are alkaloids), and would poison you if you took enough of them, even though they may be beneficial in small quantities, and in particular disease states. Even ones that are fairly harmless are generally not substances that ever were a normal part of the human diet, and thus are unlikely to stimulate the taste buds for pleasant flavors, such as sweet, salt, or umami, which have evolved so that we are encouraged to eat things that are actually foods, with nutritional value for us. The evolution of human taste receptors has not kept up with modern medical science.

---

<div class="post-metadata">

**Author:** ![Qadgop\_the\_Mercotan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/qadgop_the_mercotan/32/83_2.png) [@Qadgop\_the\_Mercotan](https://boards.straightdope.com/u/Qadgop_the_Mercotan)\
**Post date:** [November 29, 2014, 4:26pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/4 "2014-11-29T16:26:54Z")

</div>

Steroids taste bad, that’s all there is to it. My patients on prednisone or prednisolone pills learn to swallow them quickly, and not suck on them.

---

<div class="post-metadata">

**Author:** ![GusNSpot](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/gusnspot/32/436_2.png) [@GusNSpot](https://boards.straightdope.com/u/GusNSpot)\
**Post date:** [November 29, 2014, 6:08pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/5 "2014-11-29T18:08:35Z")

</div>

The reason for coated pills IIRC.

---

<div class="post-metadata">

**Author:** ![Quartz](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/quartz/32/267_2.png) [@Quartz](https://boards.straightdope.com/u/Quartz)\
**Post date:** [November 29, 2014, 7:31pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/6 "2014-11-29T19:31:13Z")

</div>

> [@Qadgop\_the\_Mercotan](#):
>
> Steroids taste bad, that’s all there is to it. My patients on prednisone or prednisolone pills learn to swallow them quickly, and not suck on them.

Thank you. Occam’s Razor strikes again.

---

<div class="post-metadata">

**Author:** ![Peter\_Morris](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/peter_morris/32/359_2.png) [@Peter\_Morris](https://boards.straightdope.com/u/Peter_Morris)\
**Post date:** [November 29, 2014, 8:41pm UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/7 "2014-11-29T20:41:28Z")

</div>

I understand they sometimes deliberately add [bad tastes](http://en.wikipedia.org/wiki/Denatonium)to medicine so that children will not accidentally swallow them.

---

<div class="post-metadata">

**Author:** ![Isilder](https://avatars.discourse-cdn.com/v4/letter/i/cc9497/32.png) [@Isilder](https://boards.straightdope.com/u/Isilder)\
**Post date:** [November 30, 2014, 11:12am UTC](https://boards.straightdope.com/t/why-do-my-eyedrops-taste-so-bad/705891/8 "2014-11-30T11:12:43Z")

</div>

Its basically an ester… These are the flavours such as banana, orange, strawberry, and so on … Since it is ester-like, there is a higher chance of being able to be tasted at very low concentration.
