For what it’s worth, some of them look a bit creepy in real life as well, but some parts that they use in TV are actually real working buildings.
Many years ago, I had the opportunity to work on the WB lot in LA. We were installing some network monitoring equipment, and had to meet up at the IT contact’s office. As I walked across the lot, towards the building, I got an odd feeling that I knew this building somehow. I did. I was a big fan of the Lois & Clark, “Superman” series. Of course, I didn’t know how I knew the building until I saw the plaque on the building that said it was the “Star Labs” building. (Superman’s doctor & science expert worked here… yes, I’m pitiful when it comes to Superman shows. 
)
The West Wing set was bizzare. “Locations” that you knew well from real life TV events, but in a location that was only 3/4 of a room, and definitely not located in the correct location relative to each other. The big kick there was the “President” riding by on a bicycle after calling the “Marine guards” to attention, and saying “Hi!”.
Both the “Star Labs” building, and the West Wing set, very much reminded me of the first time I walked through Daley Plaza in Dallas (I didn’t know we were going to walk through there on the way from the hotel to downtown), and thinking… “I know this place… how do I know this? I’ve never been here…”