I said earlier “the prime numbers without 1 all have much more in common with each other than they do with 1”, but let me make this more explicit, more formal, in such a way as illustrates why it is important to consider them as a class excluding 1.
Every prime number has exactly the same properties with respect to the structure of the positive integers, multiplication, and equality; for example, every prime p satisfies “For all a and b, if a * b is divisible by p, then either a is divisible by p or b is divisible by p”, no prime p satisfies “p * p = p”, every prime p satisfies “For all a, if p * p divides a * a, then p divides a”, no prime satisfies “There exists an x such that x * x = p”, etc. We can formalize this by noting that there are"automorphisms" of the positive integers preserving this structure by taking any prime number to any other prime number; that is, for any prime p and any prime q, there are back and forth functions f and g from positive integers to positive integers which undo each other [so f(g(n)) = n and g(f(n)) = n for all n] and which preserve multiplicative structure [so f(x * y) = f(x) * f(y) and similarly for g] such that f§ = q [and thus g(q) = p]. We can define these f and g straightforwardly, just by acting in the appropriately permuting way on numbers’ prime factorizations.
In this sense, all the prime numbers (excluding 1) are “isomorphic” to each other, with respect to the structure multiplication of positive integers. [Or just as well, we can do this extending to arbitrary integers].
However, 1 is not isomorphic to those prime numbers. It has different multiplicative properties. For example, 1 * 1 = 1, while p * p is never equal to p for any prime number.
Since all the values 2, 3, 5, 7, … have exactly the same multiplicative properties as each other, but 1 doesn’t have the same properties as them, it is very natural to restrict the definition of “prime number” to just 2, 3, 5, 7, … (which at any rate deserve some nice name in themselves), excluding 1.