For NASA’s purposes leaving the Heliosphere is the interesting point as the instruments that are still working can then return measurements on true interstellar space which we’ve never been able to do before.
If you count the Oort cloud out to 50,000 AU as the solar system it won’t leave for millennia.
OK then, design challenge for what could be used as best-case OP:
A monolithic 18x3 ft long, say, rectangular parallelepiped that lasts four million years in space. Motion control and one-time interplanetary signal to be designed later.
If our civilization is advanced enough to where we’re making a commute between the stars, why would we need a manned ship to stop and pick up the slow boat full of cold sleepers? Surely we’d have the old plans from the original ship on file somewhere, we’d send a robotic ship to retrofit the ship with faster engines. Or, build a ship that’s completely unmanned and have the AI go wake them up, then transfer everyone to the new ship.