A few random questions regarding gigantism in humans

I was reading an article about the current tallest living human, Leonid Stadnyk , which got me to thinking about his situation and about gigantism in general. I realize that these are fairly trivial questions regarding a non-trivial condition, and I hope that my curiosity does not give offense.

My first question involves dentistry. According to the article cited above, Mr. Stadnyk’s growth rate was apparently unremarkable until the age of 14. This suggests to me that his permanent teeth were probably already in place by that time. I have read that cases of gigantism and acromegaly often result in abnormally spaced teeth, which I suppose is not surprising if the jaw is continuing to grow at an unusual rate. However, in cases such as that of Robert Wadlow, where overall growth is unusually accelerated since birth or early childhood, would the permanent teeth develop more proportionately? I’ve seen pictures of the famous wrestler Andre “the Giant” Rousimoff, and his teeth appear somewhat smaller than one might expect, even though he was exceptionally large since childhood. Is tooth development affected by any types of gigantism?

I’ve also gotten the impression that certain types of gigantism not only increase the growth rate, but can also extend the period during which increased growth is possible. My understanding is that when the epiphyses of the limb bones fuse at the end of puberty, any additional height increase becomes impossible and the bones can only increase in girth, eventually resulting in acromegaly. However, Mr. Stadnyk is ostensibly still growing at the age of 33, and Robert Wadlow’s height was evidently increasing right up to his death at age 22. Does gigantism sometimes affect the fusion of the epiphyses?

This next question is no doubt one of the first problems on any Intro to Biomechanics exam, but alas this is a class I have not taken, and I’m severely mathematically impaired to boot. How does gigantism affect relative strength? If person A is twice the size of person B, then (all other things being equal), it seems to me that A would have half the relative physical strength of B. If person B is able to lift an amount equal to their own weight, then person A ought to be able to lift a maximum amount of half their own weight, since the number of muscle fibers in cross section pulling over a given distance will be squared, but the amount of weight being lifted is cubed. How flawed is this analysis?

My last question is related to the last one, and concerns the ability to swim. Again, all other things being equal, would a person with gigantism have the same, greater, or lesser buoyancy than a person half their size?

Thanks in advance for your patience. Sometimes I get weird questions lodged in my head and it’s nigh impossible to get them out short of trepanation.

R.e. bouyancy, assuming that body composition remains the same I’d think that human flesh is human flesh - density remains the same and so Andre The Giant would float the same as Tom Thumb.

In practice there might be different ratios of lean muscle mass, body fat, lungs and so on.

Strength is probably harder to figure; obviously a larger frame has the capability to pack on more muscle and the body will have longer lever arms in many movements. However at some point the cube-square law catches up and your own weight becomes a huge problem, and many giants have bone and joint problems that get in the way of them being stronger.

Andre The Giant is a good example - he was certainly incredibly strong (watch the outtakes from “The Princess Bride” where Cary Elwes is doing chinups on his outstretched arm) but no way could he jump, and he never looked comfortable just walking around.

Andre the Giant may have been strong, but not during the filming of the Princess Bride.

IMDB Trivia

Thanks Valgard and puggyfish. If nothing else, this encourages me to seek out a DVD of “The Princess Bride” and check out the extra features.*

I thought I’d bump this thread up once over the weekend, before it sank out of sight completely, just in case somebody else might have some additional insights.

Wow, this is easily one of the dumbest phrases I have ever written. Note to self: “Preview Post” is your friend.

*Totally off topic, but I had a wierd idea while thinking about Andre’s role in “The Princess Bride” movie… I have read that William Goldman had Andre in mind for the part of Fezzig from very early on. Andre’s last name is Roussimoff. Among the strange creatures encountered in the movie, and I believe in the book as well, are the Rodents Of Unusual Size, or R.O.U.S. for short… ROUSsimoff… “Unusual Size…” Coincidence? Or bizarrely convoluted in-joke?

Probably just coincidence.