At least on Buffy, werewolves are affected by tranquilizer darts. It won’t be killed by alcohol poisoning, but I think it would still feel and act differently.
Also, often when we see werewolves in TV and movies, they seem to expand in size by a factor of two or three. I don’t suppose this would affect how affected they’d be by alcohol.
Let’s see here…
Lycanthropy causes an expantion in body size by a factor of two or three.
Alcohol causes an expantion in testicle size by a factor of two or three (aka “beer balls”).
Conclusion: drunken werewolves balls much weigh about 50 lbs each.
There are way too many variations on werewolves for a definitive answer. There is a basis in some stories for plant toxins (e.g. wolfbane) affecting them, as well as the well-known garlic aversion. Some werewolves might remain drunk when wolfed-out. Others would be immediately sobered up by their rapid healing abilities. Still others might ignore the effects entirely while in wolf form, but still be drunk (or hungover) when they changed back, if they didn’t stay wolfish long enough to metabolize the alcohol.
In the Dresden-verse alone, you get some variation:
Werewolf–Someone with the magical ability to change into a wolf at will, like the Alphas. They’d stay drunk as wolves, I would think.
Lycanthrope–They don’t actually shapeshift, they’re just inhabited by a spirit of rage. They’d stay drunk, but would probably burn it off fast if they entered a killing frenzy, just like they rapidly recover from wounds in a frenzy.
Hexenwulf–They use a magic wolf-hide belt to change. They’d probably stay drunk. Of course, since the magic itself blows away their inhibitions, it might be hard to tell.
Loup-Garou–Cursed to change into a horrific killing machine at the full moon. No way booze would affect one of these things in wolf-form.
Well, there was an alcoholic vampire in Spider Robinson’s Callahan’s Place stories. He worked at a blood bank, and repeatedly got hammered on wino blood. He wasn’t a traditional vampire though–he wasn’t undead, just a member of an odd subspecies of human.
Seriously? How have I never noticed this!?
Isn’t that vampires?
I think Hal was speaking metaphorically, as in a beer making you think you’re ten feet tall and bulletproof kinda thing. My husband drinks a lot of beer, and I’ve never noticed grapefruits in his jeans. (Have I said too much? 
)
Werewolves are frequently referenced as having a garlic aversion, which honestly makes more sense than vampires having problems with it. As P.N. Elrod’s vampiric gumshoe once pointed out, “What good is something that smells bad against someone who doesn’t have to breathe?” For confirmation, I refer you to Unca Cecil on “Is Garlic Oil Lethal”.
As for wolfbane, the connection should be fairly obvious.
One theory I read on a Buffy fansite somewhere is that if a Vampire has heightened senses, then something with a really kicking smell like Garlic would be irritating for them.
Presumably, you could make one cry like a girl if you chopped onions while he was in the room.