Not that I’m a big meth booster, but alcohol is nearly as likely to make you look like that as meth is. This is a look that comes from placing pursuit of a substance above all other priorities. I have known many people who used meth or the last few decades, and none of them ended up looking like that.*
*However, many of them made poor choices on a smaller scale and alienated the people around them as a result of their use, and meth remains fairly high on my list of things that probably ought to be avoided, as it is a substance which lends itself to abuse very easily.
I know another that got much hotter – probably because she aged from 20 to 30, (which generally looks better,) kept on top of her education and employment situation, and never had to choose between meth and food or shelter.