I haven’t used the software above, but all poker sites I ever use just need the mouse. I cant think that hotkeys would offer any real advantage assuming you could interface into the poker software. Using just the mouse keys might also be dangerous. Imagineaccidently pressing leftclick to accept a $1000 bet when you wanted to fold with middle click (or vive versa)
The only advantage might be saving me typing “thank you” whenever ever someone praises my expert play, but as that happens so rarely then I can do without it