Ganymede isn’t necessarily “a bust” just because of the distance from the Sun; as I noted before, a better scheme would be to collect energy from solar radiation using solar orbiting satellites, beam the power on microwave frequencies to Ganymede (or another airless moon), and then convert the power into the UV and near-UV that plants need. However, there are a number of other issues with habitation on Ganymede, chief among them are the low surface gravity (0.146 g, slightly less than Earth’s moon), the high radiation environment around Jupiter, and a powerful magnetosphere that may interfere with normal navigation and communication tools. Unless some practical way of dealing with these hazards is found it would not be feasible to base human settlements on any of the Jovian moons regardless of food production and energy issues.
There is an assumption that comes strictly from science fiction that developing in low gravity or freefall environment will just result in taller and weaker people. However, while we have only a modest amount of experience with humans in long duration freefall and none in fractional gravity except for the short stays on the surface of the Moon, the experiments we have run with small mammals and other animals in freefall and centrifuge as well as before-and-after examinations of astronauts in mission durations of six months to a year indicate that there are far more fundamental problems besides the obvious issues of loss of muscle tone and skeletal decalcification. Humans operating for an extended period in freefall or in gravity much less than that of Earth (and the cosmic radiation environment that no reasonable amount of shielding will protect occupants from from) are likely to suffer from a variety of physiological problems including immune system dysfunction, disruption of circadian rhythms affecting endocrine and neurotransmitter systems, changes to the brain and other organs due to fluid dislocation, balance and proprioception issues resulting from adaptation to freefall, et cetera, as well as the known psychological issues from isolation, confinement, and elevated stress levels.
In reality, the notion of creating fixed bases using moons or planets as “ports” makes little sense and is essentially a trope adopted from the Age of Sail narratives of exploring the high seas and finding riches and bountiful produce in exotic distant lands. Given access to resources in the asteroid belt and other small objects such as Jupiter’s Trojan asteroids (those collected around the Jupiter-Sun L4 and L5 points), Hildian asteroids, centaurs, SDOs, et cetera, it makes far more sense to construct sizeable thick-walled habitats using natural materials such as water ice and silicates reinforced with long fiber overwraps, spun to simulate Earth-normal gravity, and with a deep inside layer of water upon which habitable and arable “islands” of low density icy pumice would float (which also provides a radiation environment comparable to that of Earth’s surface), with a large solar collector/sunshield at one end pointing to the Sun and a long anchor deployed the other direction using orbital tidal forces to maintain stability and orientation. Such a habitat could be moved (slowly) to rendezvous with resource-rich asteroids or long period comets and extract the resources for agriculture and manufacturing, and maintenance and expansion of the structure.
However, agriculture in the conventional sense is not really feasible for long term space habitation outside the orbit of Saturn where incident sunlight drops to less than 1% of solar irradiance at Earth orbit. If civilization is to exist indefinitely at that distance or to engage in direct interstellar exploration, it would require developing methods of synthesizing nutrients and probably eliminating the wasteful and complicated system of animal digestion entirely in favor of some nutrient delivery system that doesn’t require the mess and costs of agriculture, which would also require a massive retooling of the human form into something more like an organic machine. Space inhabitants of the future aren’t likely to look very ‘human’ because the human form is not readily adaptable to the space environment, and the enormous effort and energy to create a simulation of a terrestrial environment could be put to better use than growing food in the same way we have for the last twenty-odd thousand years.
Stranger