Well, Rocko’s Modern Life sometimes has human feet. There’s that foot guy that appears every so often, and the sock puppet judge. I guess to disqualify a show you’d need entire humans though…
I don’t remember any humans on the Roadrunner / Coyote cartoons. I’m a little hazy, but I think a few Sixties 'Toons lacked people too. Top Cat for one? How about Snagglepuss?
Tom (from Tom & Jerry) occassionally had a human owner, either a matronly black woman who called him Thomas or else a thinner WASP broad Both were only ever shown from the waist down as I recall.
Spongebob is lacking in human characters in its day to day episodes (though there’s at least one where they show a person).
All three seasons of Transformers: Beast Wars and both seasons of Transformers: Beast Machines would qualify. Not a human in sight, though there were some proto-human neanderthals in a few episodes.
Spongebob Squarepants doesn’t have any humans in it on a regular basis. Sometimes a hand shows up. There’s a ghost that’s a human, I suppose, but it’s mostly sea life. And a squirrel.
No, Seven Little Monsters have their human caretaker, whose name is Baba Yaga, I think. (I’ve only watched it on occasion when I’m waiting for Frank and Frank.) Other human characters have appeared as well.