You’re right, Jadis. Since the OP stated it was taken for OA, I misread it as chondroitin.
Chromium picolinate: No evidence for the claims for weight loss, body fat reduction, muscle building, increased metabolism, appetite reduction, cholesterol reduction, blood sugar regulation, energy and stamina booster, and diabetes helper. There are two studies on which much of the chromium craze has been based. A 1996 study showed that it did increase muscle mass in animals, not humans. A 1989 study showed a small, insignificant increase in lean body mass. Four studies conducted between 1992 and 1996 failed to confirm that chromium picolinate supplements can result in increased lean muscle tissue.
A recent study found that it can damage chromosomes, but that appears due to the picolinate, not the chromium.
However, new research shows it is useful in sprint performance in runners. Chromium is a trace mineral that helps your cells use carbohydrate for energy. With insulin it allows sugar to enter the cells.
It has never been claimed to help OA.
However, as far as glucosamine is concerned, the March 2001 issue of Health News, reporting of an article in the January 21 Lancet, stated that a study of 212 people with knee OA, the half who took glucosamine did not show loss in the cartilage, while the other half did. Glucosamine users also reported less pain and disability.
There are definite medical reasons why glucosamine can help. it is a component of a substance ur bodies use to make and repair cartilage, and it is absorbed and distributed to the joints, according to other recent research.
http://www.consumerlab.com fond that glucosamine levels in some pills don’t match the label claims.
I know all this stuff about glucosamine is off the OP, but it is this substance, not chromium, that can help OA.