Good point. I think some people overlook the fact that many people who were named here actually do have training, either at university or through years of work with a group like the Groundlings.
Did Mrs. Cheesesteak meet or get to know any of those actors while there? I know, most colleges are large enough that just because you happened to go there at the same time as person (X) it doesn’t mean you even crossed paths with that person. But it sounds like a small enough niche-style school that maybe everybody knew each other.
She met them, but not really buddy buddy with any of them. She didn’t really know PSH at all, she thought Adam was much funnier at school than on SNL, and Erbe I’m not sure. She dislikes Erbe as an actor, but I’m not sure if that started from seeing her work at school, or just thinking “SHE graduated from Tisch? Bleh!”
TBH, Adam gets mentioned by me only to needle her a bit, like when my son is watching Pixels.
On a first name basis, eh? Not too shabby! 
And there was Daniel von Bargen, who could play a genial dope (Mr. Kruger on “Seinfeld”) or a ruthless, malevolent bastard (Sheriff Cooley in “O Brother, Where Art Thou?”).
I don’t know if you’d call martial-arts-movie superstar Jackie Chan a “comedian”, but he’s made a lot of comedy movies and his action-hero persona is more funny than dramatic. So I was surprised and impressed by his performance in his far-from-always-comic role in the 2010 Karate Kid remake.
I’d have to put Nathan Fillion and Alan Tudyk on that list–both affable goofy nice guys who can turn on a dime and make you wet your pants in sheer terror.
Another movie in English where he takes a dramatic turn is The Foreigner with Pierce Bronsan. I also recently saw the latest Police Story, which unlike the previous ones is not comedic at all. I think that as he gets older he is really wanting to show his range.
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Although I agree to a certain degree with this idea, Good Will Hunting is arguably an exception as although his character plays it straight for most of the film, there is comedy mixed in, and he did win an Oscar for it.
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John Candy was great as a romantic lead in Only the Lonely. The scene where he tells his mother how she keeps wrecking his life is great.
I always think of him as the headmaster of the military academy on Malcolm in the Middle
Fred MacMurray is primarily a comic actor (and liked it that way), but when cast in serious roles, he hit it out of the park in Double Indemnity and The Apartment.
Buster Keaton did a fine job in a dramatic role starring in The Awakening (1954,TV episode)
