My new (this June) computer has developed a quirk: When I go online, with AOL, and pull out the Favorites drop-down menu, and select a site, I hear the sound effect Windows uses for “critical stop” unless there is a CD or a DVD in the D: drive. A dialog box on the screen tells me to put a disc in the drive. Why does it do this? 
The program you are running is looking to the CD drive for some data. When it doesn’t find it it gets pissy.
Why is it looking there? I have no idea. Perhaps during your install you told it to run from the CD (just guessing and it is rare but I have seen some installs which allow you to opt to run from the CD rather than moving the program entirely to your PC).
If I were you I would delete the program and download the latest version online and install from that.
Hopefully that will sort your problem.
ETA: AOL sucks…as a matter of principle you should chuck it.