Well, the M is right.
Maybe:
Little Women go mad as rabbits this season (5)
MARCH (double definition)
+++++
Experimentally misplace ice outside: this could lead to a disaster. (8, 5)
Maybe better:
Experimentally misplace ice outside: this could lead to an environmental disaster. (8, 5)
Dayuuhhhh is Chernobyl part of the answer?
No Chernobyl, but the CH start is right.
Hint: anagram/container
If it was (5, 8) instead of (8, 5), then CHINA SYNDROME might work…
CH + (anagram) + ???
Is the first word a location?
No location. The outside word is a synonym for ice, as in “Please ice the beer so we can drink it later.” The anagram is indicated from the text of the clue. I like to almost always have any cryptic anagram to be directly a word or words taken from the clue.
CHEMICAL SPILL (CHILL around MISPLACE anagrammed)
Hello, Poppets! Well, Hello, messily insured Poppets! (5’1)
I guess I did that wrong. Let’s try:
Hello, Dolly! Well, hello, Dolly, you’re a mixed up mess of insurance it Seems (5’1)
LLOYD’S (Dollys anagram)
Cram into a set on this California city. (10)
Sacramento (CRAM + anagramed A SET ON)
———-
In her remarks the Senator mentioned pain and suffering (7).
TORMENT (hidden word)
When the mathematician made a thong go-go, he got to this degree. (3)
NTH (thong - go)
Seven and seven equals elevated orb (8)
“Seven and seven” refers to something else besides math.
HIGHBALL (double definition)
+++++
Llama’s great play could send it here? (3-4, 4)
All-Star Game (anagram)
+++++
Did you say you’ve got a mess o’ the Leo, Ma? You may be entitled to compensation! (12)
Mesothelioma (homophone)
———
When the Titanic went into the sea, a band on deck was left behind (7)