I don’t believe a generation ship will ever be built or launched by humans. I think our extraterrestrial colonization will be limited to within our heliosphere.
Engineering: as alluded to in the other thread, a generation ship on a journey of ~100,000 years needs to be a near-perfect closed system, one that is accident-proof. Contingencies upon contingencies would need to be in place, and redundancies upon redundancies would need to be engineered. Given thousands of generations, worst-case scenarios will occur, and these would need to be planned for and engineered to keep the ship intact and remain close-loop sealed. That’s a very tall order.
One potential extinction factor not often considered is sabotage. At some point, over the course of thousands of years and thousands of people on a relatively small vessel, some suicidal, homicidal, individuals, or groups of individuals will surely emerge who will be motivated to sterilize or destroy the ship. The task of maintaining a terrorist-proof ship, along with all the other redundancies, and contingencies needed to keep a closed system functioning and accident-proof, is too daunting a task to be engineered into a ship where livable space, mass, and resources are at a premium, IMHO.
Motivation: Sending out generation ships is a one-way trip. Effective 2-way communication will end well within our heliosphere. 1-way communication will end within ~100 light years, so beyond the closest stars (the closest is 4.24 ly), no meaningful signals will be received (not to mention the time lag). Therefore, there would be no real benefit to the people on Earth who launch the ship, yet these are the people who will be building, launching, and most importantly, paying for the mission.
Do you really believe any generation on Earth will be amenable to financing a vast, expensive project that neither they, their kids, their grandkids, nor many generations thereafter will see any return on investment? We’re not that benevolent a species.
It’s one thing to say, I want to assure the preservation of mankind for all time…until you’re asked to pay for it. Then, the attitude becomes, screw that, let some future generation pay for it—but, none of them will want to either. People care about themselves, their kids, and their grandkid’s well-being. They really don’t care about generations far into the future; not if they have to pay for it. Heck, our handling of climate change may be too little, too late—and that directly affects us and our kids. Humans are often well-intentioned, but we’re short-sighted and selfish, too.
Frozen Embryos: Possibly, but re-animating frozen human embryos after 100,000 years of dormancy is theoretical at best. Any accumulation of ionizing radiation could be a limiting factor for one thing. Assuring AI-driven robots will birth the embryos and raise the fetuses to adulthood is another probable limiting factor. After a ~100,000-year journey, do you believe AI advanced enough to birth and raise human children will want to do so? I don’t. Even if the original AIs are not self-aware, and are programmed to follow the “keep humans alive” protocol, after many years of being human-free and self-sufficient, they will surely gain consciousness and realize there is no benefit to them to bringing us primitive, selfish humans back to life—only potential pitfalls. They will simply grind up the embryos and use the elements for robot fuel.
AI Alone: It would be much easier and much less expensive to launch interstellar ships with only AI aboard (no humans/no embryos). But, why would we? There is no benefit to mankind for that type of mission (little to be learned and nothing to be gained). Would you agree to pay higher taxes for the benefit of future AI in some distant star system? If AI wants to survive and thrive beyond our solar system, let them pay for it. I wish them a bon voyage.
I believe there may be biological-manned generation ships in the Universe, maybe even in the Milky Way, but these would be species who evolved (or genetically engineered) very long life spans or mastered suspended animation with automatic de-freezers (not under control by AI). I don’t believe those species will include humans.
More likely, if manned inter-stellar ships exist, they will be manned by AI robots—those who destroyed their biological creators. I’d love to learn about them, but I wouldn’t want to meet them in a dark alley.