Do compassion and empathy have a legitimate place in setting political policy?

Your friend is mistaken on two counts. The premable is not a grant of power, and an exercise of federal powers can’t be held unconstitutional because it violates the preamble.

Jacobson v. Massachusetts, 197 U.S. 11 (1905).

The General Welfare Clause that your friend should be looking at is in Article I, Section 8, regarding congressional power to tax and spend. That section explicitly says that Congress has the power to provide for the general welfare:

Emphasis added. Moreover, Alexander Hamilton argued in the Federalist Papers that the discretion on what consituted the General Welfare for purposes of spending is solely within the purview of Congress:

Federalist 21

pravnik you found the stuff I needed! I agree that the Articles of the Constitution clearly outweigh the preamble.

Thanks everyone for the good arguments!

Correction: should be Hamilton’s Report on Maunfactures.

ETA: Glad to help.