Good website for hotel rates/recommendations? (San Fran)

Can anyone recommend a good website for finding cheap hotel rooms at fairly good hotels, along with reviews to be able to determine ?

Alternatively, does anyone have a recommendation for a good hotel in San Francisco? I was browsing around on hotels.com (which may be exactly the answer to my first question, unless there’s another much better site around) and they seem to be either <$120 per night and look seedy or >$380 per night super-expensive. I’m looking for something in the middle… $250ish per night maybe?
Ideally something romantic and comfy, as opposed to chique and trendy.
Thanks.

I’ve had great luck with hotels.com.

We used Hotwire a couple months ago for a weekend trip to San Francisco. We wound up at the Grand Hyatt for about $150 per night, including taxes.

We’re in SF overnight once or twice a month and spent a week on vacation there last November. We’ve stayed in just about all the big name hotels and the smaller boutique ones (mostly the trendy ones.)

For the past year we’ve stopped booking hotels and are now pretty much only booking apartments, mostly through VRBO and craigslist.
Every apartment we’ve stayed in has completely surpassed our expectations. And we haven’t paid more than $125 a night yet.

Our last apartment was in Opera Plaza, was absolutely gorgeous and spacious, and was $100 a night. It was during the Tour de France and my husband was bummed he’d miss a couple of legs of the race, until we got to the apartment and realized the cable included a DVR with plenty of space to record (we deleted it afterwards.)
At another the owner left us a bottle of wine, and at another the owner had placed fresh flowers around the place. They’ve all been very comfortably appointed, making them all very romantic feeling to us. We just feel more relaxed, more ‘at home’. Plus we can cook, etc.

We look for apartments in the heart of the neighborhood we plan on spending the weekend. Most have some kind of parking arrangement for us.

We do usually have to leave deposits, but really, that’s not an issue. Honestly, I may never stay in a hotel in SF again and it’s something I definitely recommend.