There are plenty of things I have no particular interest in, or think they wouldn’t be worth the cost. But things I’d turn down even if a bunch of friends were doing them, and they were paying my way? That’s tougher.
Let’s see… Drinking kupe luwak coffee, eating fugu, hiring a prostitute… Can’t come up with much.
Absolutely nothing that involves jumping from a great height. I don’t care if there is a bungee cord or a parachute or whatever. I don’t trust it.
I also have no interest in ever visiting Las Vegas. Actually, I won a trip to Las Vegas and was not in the least disappointed about being unable to claim it (it was at a beer festival in Portland and they were assuming the winner would be someone who lived in the Pacific Northwest, which I don’t). It’s probably one of the few places that I’m not at least interested-in-enough-to-claim-a-free-trip.
I am all right with climbing smallish mountains, but I don’t have any desire to climb a very big one.
Wow, a lot of people seem to be cribbing off my own anti-bucket list:
An airplane falling apart is a different matter, though… although I’m trying to avoid those as well.
I’m not even getting my ears pierced, so there 
Some of us have already done some traveling to other continents… it’s not something I’d rule out, but I don’t view it as a requirement, either, at this point.
I have no interest in doing anything physically risky.
No interest in social activities with weird rules, like no verbal communication allowed.
No interest in Participating in or witnessing sexual activities involving pain, sharp things, blood, bruising, or humiliation.
No interest in isolation chambers.
No interesting in camping out (worth repeating).
No tattoos, piercing, or other body modification.
No interest in removing or trimming my body hair except as medically necessary.
I will not climb a mountain, bungee jump, or jump out of an airplane.
I will not go again anywhere that requires a plane trip of more than 5 hours (unless someone stakes me to 1st class).
I will not visit Disneyland, or Vegas.
I will not attempt to visit any of the 17 US states or 3 Canadian territories I have not already visited.
I will not hike the Appalachian trail, although I almost wish I had done it younger.
North America is big enough, and has plenty enough to offer, that I can spend my entire life doing these things right here.
Another vote for skydiving, bungee jumping, or any other supposed “thrilling” activities related to heights or falling.
And the tattoos and piercings.
Yeah, I think this thread is for something stronger than just “have no particular interest in.”
It’s not just the things you don’t want to do; it’s the things you want to not do.
No body modification that’s not medically necessary.
No parachuting not related to catastrophic aircraft failure. Same for flying suits.
No shipwreck diving. Damn things are spooky.
No cow tipping. Seems rude, and belligerent bovines are not my animals of choice.
No dance marathons.
No eating contests. Especially smelt eating contests.
I will not be visiting North Korea. Nor North Sentinel island.
No cloning my pets.
Well, visiting Wuhan, China is now off my list…
Times Square, New Year’s Eve.
I’ve gone sky diving three times. It felt like flying.
Would I do it again? Hell, no! That’s fucking dangerous!
And another “oh hell no” to bungee jumping. That never appealed to me, or my back.
Preach it.
I’ll add:
Climbing any mountain.
Zip lining.
No swimming of any sort.
I’ve traveled enough in my life and at age 72 have no desire to now get on a plane that leaves the U.S. boundaries. Too long and too uncomfortable. We’ve made a few trips to the east coast, and that’s about as far as I want to go, even in first class. My wife really, really, really wants to go to India, which I’m fine with. . .for her, not for me. Find a friend and go, already. Of all the places in all the world that I would endure the misery of that long a trip for, India is pretty much dead last.
My brother did enough sky diving for both of us. I went up with him on the plane, but came down on the plane. That’s close enough for me.
I have no desire to go into the interior of China. I’ve been to Hong Kong and Macao, close enough. Ditto for Vietnam. I avoided the place during the late unpleasantness, want to keep avoiding it.
No desire to go skiing. No desire to get a tattoo. No desire to use any drugs. No desire to own a gun. I’ve shot them, but who wants one?
And cruises are not bad if you go to interesting places.
Now I’m all hungry for smelts.
Shell out for business class and you’ll be fine. Went that way to Hong Kong, and I had plenty of room. Start by going to England where they speak the language, more or less. Low stress.
Course I’m from New York so I thought Hong Kong was great if a little empty. 
North America is only geographically large. Culturally it’s relatively uniform.
No piercings, tattoos or other body modifications that aren’t medically necessary.
No travel to Africa, South or Central America, Mexico, the Middle East, India or China. Heck, include no Asia at all.
No mountain climbing. With my current body, not likely to climb anything, actually.
I’ve been on one cruise. That was enough.
Ditto to others who’ve mentioned Las Vegas.
I’ve gotten to go on two National Geographic Cruises–to Baja California and to Antarctica–and they were flippin’ amazing. So yeah, the standard cruise experience doesn’t sound great, but some cruises can be sweet.
As for me, I love needles the way dogs love fireworks. So tattoos are right out, and I’m not really searching for alternative ways to get heroin on my bucket list.
Even though I would have no problem with skydiving, there’s no way I would go bungee jumping. I guess I trust the laws of aerodynamics more than the laws of elasticity.