Yes, it did happen to me once. Fortunately, I was driving at relatively low speed in the righthand lane and was able to come to a stop, put on the flashers, and dig around for the bits and pieces, and jury-rig them together until I could get home and get my spares.
If I’d been on the freeway I might have been thoroughly screwed.
Since then I perform regular inspections of the specs.
I have also had a pair of fitover sunglasses spontaneously self-disassemble, but I don’t pay nearly as much for those, I tend to be hard on them, and their abrupt loss was annoying but was not going to result in catastrophe.