Hear hear, Tamerlane. I live more-or-less comfortably in precisely that salary range in one of the tonier towns in the affluent county immediately north of San Francisco, and my girlfriend lives in a hip, central part of the city on a slightly lower income. Granted, we both live paycheck-to-paycheck, but we’re hardly living like Dickensian waifs.
I also lived in San Diego for five years between 1994 and 1999, and honestly, your dollar goes a LOT further there. You do really need a car, as the bus system in SD is a sick, sad joke. There’s a commuter light rail system which I never used, but is apparently not bad if you’re zipping up and down the coast. All in all, Sandy Eggo is a nice little town; the weather is pleasant to the point of monotony, people tend to be laid-back (if a little conservative), and there actually is a lot to do.
The downsides? Culturally, San Diego is still kind of a small town. That’s not always bad, since you get to know the people in your scene pretty quickly, but it definitely starts to feel like a small pond after a while. However, geographically, it seems to go on and on, with no sense of structure, just one big sprawl. Much like that sentence… There isn’t much of anything that’s very old, and most of the architecture seems like a shoddily-constructed afterthought.
There are some really great neighborhoods in San Diego, particularly north of downtown, like Hillcrest, Mission Hills, and North Park. I hear that Golden Hill is the up-and-coming hipster 'hood, although I think its also immediately underneath a flight path. Little Italy is newly revitalized, also, and apparently is becoming habitable once again. In those nicer neighborhoods (such as Hillcrest), the cost of living will rise closer to that in, say, San Francisco, but all in all, I’d say its still less expensive. Lsura, if you wouldn’t mind, maybe some more info about your field and your interests would be helpful? Given what you’ve said so far, I’d heartily recommend a visit to the southland; you may love it. Lots of people do, just not me.