I got lost in Toad Town. 
I don’t play games where you have to navigate through dungeons with a view like what the character sees- I get hopelessly lost in those. I’m fine if there’s an overhead view, a la Dragon Quest.
In real life, I have lousy spatial skills and get lost a lot. Not surprising that it happens in video games, too.
I haven’t been very lost since Zork (“You are in a maze of twisty little passages, all alike.”)
Years of practice and my Male Sense of Direction Instincts ™ keep me from getting very lost in video games. I also have a healthy exploration desire that requires me to check out every direction to see what’s there.
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The Great Crystal, on the other hand, nearly drove me to drink. Everything looked alike, there were cryptically named and numbered switches and forcefields, and the “map” was just a picture of the crystal as it might look from a distant airship.
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Yep…but I don’t feel too bad about getting lost in there, because of that. They WANT you to get lost. (At least, I assume so.)