The problem is, every damn time humans have tried to wipe out a specific niche in the foodchain in a localized area we screw it up.
What will probably happen
The anopheles die. Total mosquieto populaton declines due to that.
Birds/other mosquiteo predators eat the same number of mosquis as previous years FURTHER depressing total mosquis populations.
Fewer moqsuis survive to reproduce.
Next year:
Fewer mosquis, even less food for birds birds start dying.
Population pressure removed on other insecets.
Or with a reduction in mosquiteos as a food source birds eat more populations of other insects… screwing up that ecological niche.
CRorex, perhaps, but I don’t think the balance is all that delicate. After all, we doused Seattle with DDT for how long to eradicate malaria there, and we still have plenty of birds in the region, again despite the mass reduction in the insect populations and the supposed harm DDT does to bird shells.
As the HEGs are even more narrow-spectrum than any pesticide, only targeting one species, I don’t see the huge risks here.