Inspired by this thread
Ignore the issue of getting them to the moon in the first place, and assume you launched all the nukes in the world at the moon at the same time. What would happen? Would the moon explode? Crack but remain intact? Suffer little or no structural damage? Would the earth be in any danger, either from orbiting into the remaining dust/debris, nuclear fallout, or anything else? Would it make a difference if they all hit the same spot on the moon or were spread out across the lunar surface?
Humans, as horrible as we are, thankfully aren’t nearly as powerful as we like to think we are. The moon is used to getting nailed by impacts much larger than we can ever hope to dish out. Nuclear strikes would leave big some craters and surface scarring but not much else. You have to appreciate the scale of your enemy here and even though the moon seems small, your nuclear bombs are still just ants biting an elephant.
The moon’s biggest strong suit in a fight is that it has little to lose. It was created by debris cast off from some other planetary body (probably earth) early in the history of the solar system. All of those fragments got pulled together through gravity to form our dear luna.
The moon is like a the undead however. You can’t really kill it or hurt it because it already is just a bunch of rocks and dust held together through gravity and they will tend to stay that way in the long-term. We don’t have enough nuclear weapons on earth to even make it really mad let alone blow it up.
This is a disturbingly popular question this board and others however:
http://cosmoquest.org/forum/archive/index.php/t-20361.html
http://www.kongregate.com/forums/2-off-topic/topics/165532