In this case, it would be the collective deregulation of antibiotic use over a population of millions that would and should be a cause for public concern. I still know fairly intelligent people who seek out antibiotics for a cold, ferchristsake.
Anyhow, my major point is our technology (that is, applied science in all facets of our life) has created a world that couldn’t function without at least a robust federal government. And even at this point, I feel our current federal and state organizations seem crippled or even paralyzed by cumbersome and tedious bureaucracy or pathetic partisan spite to respond fast enough to an ever increasing pace and complexity of the modern world.