Large universes will almost always show noticeably large numbers of events of almost anything you can think of. (Yes, 19 homicides might be noticeably large.) Within those events, there will be clumping just by chance in addition to any possible clumping because of a real effect.
The real world example that gets the most press is cancer clusters. In a population of 320 million - the whole U.S. - there will be millions of cancer cases and hundreds or thousands of even rare cancers, sometimes in close proximity. So is something causing those cancers or it is just random statistical clumping?
The only thing you can be 100% certain of is that the people involved in those clumps won’t believe - sometimes rightly, sometimes wrongly - that the clumps are merely statistical, even if they are significant.
I’d make statistics, along with elementary economics, mandatory high school courses.