Hi everyone. I have a solution for you. I had this problem from about 2005 to 2009. Uncontrollable itching; no sign of a rash. I would itch until there was blood. It started out in a very small area on my upper left outer calf but as the months and years went on, it spread to both calves and outer thighs as well.
I went to many different doctors: two dermatologists (one thought it was all mental; the other said he could not diagnose the itching without seeing a visible rash), an allergist, a neurologist, and a few other doctors I forget.
Finally, I just wrote down every single thing that people recommended online and went through and did them all. The solution that worked for me was Vitamin B. I started taking liquid Vitamin B (liquid because apparently the body absorbs it better). I can’t find the original post now but from what I recall, the person said that, for whatever reason, your skin is not allowing your legs to breath or sweat properly, and that you may have trouble absorbing Vitamin B. He or she recommended Vitamin B supplements so I started taking them and after maybe a few days, I was walking around and felt a foreign sensation in my legs. It was air hitting the sweat beads and cooling my legs. I realized then that the original poster was right. My legs hadn’t sweated in so long that I forgot how it even felt.
SOLUTION: Liquid Vitamin B and increasing the amount of Vitamin B-rich foods in your diet (eg, red meat).