Ybor is okay, there are several good bars and restaurants. I suggest you go on a Friday night. Saturday nights are a bit over the top, and lately there have been too many violent episodes on Saturdays. Hotels may be a bit expensive.
Hyde Park Village, for that upscale shopping experience
Florida Aquarium/Channelside, not a bad way to spend an afternoon
Tampa Museum of Art in downtown Tampa
Clearwater Beach, very nice
In St. Pete:
Baywalk, cute little boutique-type stores & restaurants
Dali Museum, an amazing must-see
St. Pete Beach - prettier and quieter than Clearwater Beach
In Sarasota (@1 hour South of Clearwater):
Ringling Museum, pretty nice
St. Armand’s Circle, more upscale shopping
Marie Selby Botanical Gardens
Note: While it’s possible to get around each city using the bus system, but I don’t recommend it. It’s a huge waste of time, and overall, not a pleasant experience.
Enjoy your visit!