Raising Arizona.
Star Trek II: The Wrath of Khan.
Star Trek III: The Search for Spock.
My bad - I thought for sure there was a character in that movie that was suppsoed to be Alice B Toklas.
Philip K. Dick’s The Man in the High Castle. The character described by the title doesn’t appear until the very end.
Fear not. Rhymers are easy-going and not given to ranting.
I’ve got one, it just so happens to be my favorite movie of all time: Dr. Strangelove or; How I Learned to Stop Worrying and Love the Bomb.
The titular Dr. Strangelove actually has a relatively minor roll in the story, albeit a hilarious one.
Waiting For Godot
And, it just occurred to me,
The Gospel of Matthew
The Gospel of Mark
The Gospel of Luke
The Gopel of John
I thought of those when I opened the thread. They’re odd cases, though, as I seriously doubt their authors thought of them by those names (even in Greek or Hebrew).
Does Charlie’s Angels count?
I wouldn’t think so. Charlie’s Angels are the stars of the show.
But Charlie is not. I wasn’t which way that would go.
Alien
Jaws
King Kong
Saving Private Ryan
Jesus Christ, Superstar (I think the main character was Judas)
Amadeus
Twelve Monkeys
Rosemary’s baby
Sleuth (I presume the title refers to the character played by Alec Cawthorne)
The Lady Vanishes
There was a recent thread here about the Nabokov novel Lolita, whose protagonist (and narrator) is, of course, not Lolita herself but Humbert Humbert.
I dunno, it seems to me that Jaws and King Kong were the main characters. If I were to give the one-sentence summary of either of those movies, I’d surely mention the big animal, but not necessarily any particular human.
I don’t think “twelve monkeys” is the name of a character in the movie.
JCS I’m ambivalent about. I can go either way on whether Jesus or Judas is the protagonist, but there’s an argument to make either way.
With King Kong I’d say you’re just plain wrong. It’s Kong we’re meant to identify with just as much as Ann Darrow. Certainly it’s not the filmmaker.
Since there is no character named “Sleuth” or “Lady” in the last two movies, I’d count those out as well.
I thought that post would get you ranting for sure. 
Moby-Dick (the protagonist is Ishmael)
The novel The Lightning Thief. Percy Jackson is the main character and is accused of being the titular thief but the actual thief is a minor character whose identity isn’t even revealed until the last chapter.
The movie adaptation, on the other hand, doesn’t count, as it was released with the unwieldy title Percy Jackson and the Olympians:The Lightning Thief:A Quinn Martin Production or something like that.
Terror of Mechagodzilla - Nobody but the big G is the protagonist of any of those flicks. Sure, there’s a bunch of ineffectual scientists and military guys wasting most of the screen time, but Godzilla is the star.
Being John Malkovich.
They are descriptions. And there are plenty of other descriptions in this thread that you didn’t object to, e.g. The Merchant Of Venice, The Thin Man, The Third Man, and so on. I’d say that Sleuth and Lady are as valid as they are.