I don’t see why we couldn’t do it, given enough time. (Humans take such an annoyingly long time to reach reproductive maturity.) The OP specifies “fully functional” adults, so that would mean that simply breeding the tiniest humans that we can wouldn’t have satisfactory results. Usually if people are really really short, it is because of dwarfism or some other type of disorder. Much like breeding dogs, we wouldn’t only be breeding for size, but for other characteristics as well.
Now if we went ahead and started a breeding program with really short people who had no health problems or genetic disorders…
(Note: I don’t know much about genetics, but I’ve read a bit about dog breeding. If I get something horrifically wrong, please be kind.)
Here’s a scenario:
Let’s say that there is a worldwide agreement to send a group of colonists to Mars in 100 years. That time will be used to develop the necessary technology, of course, but it will also be used to breed extra-small colonists. Since 100 years is only enough time to have 4 or 5 generations, we wouldn’t reach the “lower limit of human size,” but it would be a start.
A few assumptions:
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Everybody who can be in the program will want to be in the program. Women will bear multiple children via artificial insemination. There will be no major fertility problems. Nobody dies before being bred.
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No genetic engineering will take place. Only good old-fashioned breeding will be used. Also assume that no major developments in genetic testing will occur. Like dog breeding, the program will depend on a variety of types of testing, but will also have the elements of trial and error and dumb luck.
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For simplicity’s sake, assume that the products of each generation will only breed with each other.
So the Program Engineers would launch a worldwide search for 1000 initial candidates for the program, say people 17-19 years of age. Call them Generation 1. The goal is to create a group of people of minimum size with excellent characteristics.
First, all people who have a “disqualifying factor” are eliminated. Anyone with any kind of genetic disorder is disqualified. Anyone who is, or has a good chance of being, a carrier of a genetic disorder is out. Anyone who has a strong family history of disease is out. Anyone who is not themselves healthy is out. Anyone who does not meet a minimum standard of intelligence is out. And so on.
Of the people who are not automatically disqualified, the shortest will be identified.* Let’s say 1,000,000 very short viable candidates are chosen.
The candidates will be then ranked according to various characteristics. Of course, height will be one of the most important ones, as will be a family history of shortness. Other desirable characteristics will include intelligence, creativity, athleticism, and all the usual stuff. Undesirable characteristics will include anything that might be unwanted in a pioneer society, from laziness to family history of twins.** (What might be considered desirable or undesirable is a whole 'nother thread.)
Then 500 male and 500 female candidates with the best combination of stature and characteristics will be chosen.***
Let’s say that G1 is bred over the course of a decade.**** Each breeding pair will have an average of 4 babies, giving us a G2 population of 2000. As they grow towards reproductive maturity, they will be evaluated and tested. A certain percentage will have disqualifying factors and will be dropped from the program. The remainder will be ranked like their parents, according to stature, good characteristics and bad characteristics. The top 500 males and 500 females in G2 will be identified and bred, producing G3.
Then G3 will be evaluated, and the top 1000 will be bred to produce G4. G4 will produce G5. Assuming an average generation length of 25 years and assuming my math is right, the G4s and G5s will be getting on a spaceship to Mars. The G5s will attain their adulthood on the trip, so you can consider the G5s the colonists. No new colonists will arrive for at least 100 years.
G5 will be the first generation to choose their own reproductive partners. Meticulous records will have been kept and the cultural taboo against incest has been maintained, having been modified to discourage romantic feelings between genetic “brothers” and “sisters.” In other words, G5s and their offspring will not be bred according to any program, but will avoid inbreeding as much as possible. Since there will be no Engineers running things, all offspring that can reproduce will probably do so. The population will grow.
So fast-forward to the time when G5’s grandchildren and great-grandchildren are being born. What will the Martian colonists look like? How small would they be? Will they be genetic minisupermen? Will new genetic disorders have arisen?
- Would it be the shortest overall, or the shortest relative to their own populations? I’d vote for the latter in an effort to maximize genetic diversity. A short Norwegian might be taller than an average pygmy, but if he manages to be short among the Norwegians, you know he has some strong shortness genes in there. Mate him with a short pygmy, and there you go.
** Nothing’s inherently wrong with a family history of twins, but multiple births are inherently higher risk than single births, so we might as well breed it out of our colonial population.
*** Is a G1 population of 1000 enough to ensure sufficient genetic diversity?
**** Would it be better to have each breeding pair produce multiple babies, or to switch it up, having each baby produced by a different set of parents?