The Philadelphia Inquirer often abbreviates Montgomery and Delaware County, PA as Montco and Delco. I have seen Chester County as Chesco, but less often. Bucks is short enough to not need the abbreviation I suppose.
Des Moines is universally abbreviated as DSM, its airport call sign…except for the Register, who always calls it “D.M.”
Bellingham, WA becomes B’ham. Salt Lake City becomes SLC. San Luis Obispo is SLO.
That’s how quite a few people say it, though, so no cringing here. I’d spell out the pronunciation as “BOOD-KE” (BOOD as in Budah, and KE as in kettle). Although, if I heard it pronounced “gringo”, like how I’d say it based on the above pronunciation guide, I’d be cringing, too!*
On the buses in Los Alamos, they say “LA BUS” on the front and sides. I’ve been looking at them every day for two years, and cracked up last month because I was looking at one long enough to realize it said “THE BUS” on the front**.
*I retyped this two or three times, and can’t get it to not look snarky. That’s not my intent.
**For those that don’t know, la is the Spanish feminine definite article (the).
Strangely enough, I know of no abbreviation, journalistic or otherwise, for Poughkeepsie.
Surely “Pookie” would do the job? 
For a while, I went to the University of Evansville (Indiana.) That was often shortened to E’ville. One student bought a big window decal, but it was too long for the back window of his early VW Beetle. He had to cut out a few letters. It finally fit when he got down to
UNIVERSITY OF EVIL.
Toronto is often “T.O.”
“Metro” was often used, but it referred specifically to the former regional government known as Metropolitan Toronto. There was a local City of Toronto government under it, as well as governments for five other cities. All of these were forcibly merged in the late nineties, and there is now just one unitary City of Toronto. (Plus various and sundry surplus council meeting places. The attached offices are still in use, of course, but the actual council chambers are now unneeded. I believe the council chambers in the old Metro Hall are now a call centre.)
What about Pensacola, Choctawhatchee Bay, Tallahassee, Wewahitchka, and Apalachicola?
In Idaho, Pocatello is called “Pokey” or “Poky”. Sometimes Twin Falls is simply “Twin”. Couer d’ Alene is “CdA”, though this appears only in print. I’ve never heard it spoken this way.
Today I noticed they used “Naugy” for “Naugatuck”. Very rare.
Cleaveland is now Cleveland. 
But when they drop the first part of such names, “Heights” alone means Cleveland Heights.