Players whose record was ruined by playing with an all time great

From this year’s Wimbledon thread:

I think there might’ve only been one QF loss, but that’s four finals losses and three semifinal losses. More significantly, perhaps, is that almost every single time Roddick got that far in a tournament, he lost to Federer. That’s seven losses to Federer out of his 10 best major results, with one win and two other semifinal losses (one in crazy circumstances).

Nadal was #2 by some time in 2005, after he won the French Open for the first time.