KSRV in Ontario, Oregon which is in the Snake River Valley.
Seattle used to have a radio station KILO that catered to tokers and such. Now a station in Colorado has that call sign. I’m sure there’s no weed users there.
Classic / hard rock station WAPL’s call sign is a reference to its location in Appleton, WI.
TV station WBAY is located in Green Bay, WI.
I believe that they use an updated version of the original one.
KBAD broadcasts from Badlands Pawn in Sioux Falls, SD which is nowhere near Badlands National Park so I don’t know why it is called Badlands Pawn.
Including the San Francisco stations mentioned above, there’s also KFRC. KSJO is in San Jose. KGO in San Francisco was originally General Electric, Oakland.
KCRW, the NPR station associated with Santa Monica Community College, stands for College Radio Workshop. Though occasionally they like to claim that the C stands for Corsairs, the school’s athletic teams.
Channel 10 television in Sacramento is KXTV.
WYSO, Yellow Springs Ohio, (NPR affiliate).
KCAW, *Raven *Radio, Sitka, Alaska. (Also NPR I believe)
WAVY-TV in Hampton Roads, Virginia, recognizes that Virginia Beach is on the Atlantic oceanfront. Has an appropriate logo, too.
Similarly, WDIV is Detroit’s channel 4.
Public Radio station in Detroit is WDET.
WAMC, the public radio station headquarted in Albany, NY, started out as the radio station for the Albany Medical College.
After reading all the other posts, I don’t think I am breaking the OP’s rule by pointing out that 1440 AM WNFL is, of course, in Green Bay, Wisconsin.
WAMU is at American University
WBEN in Buffalo, NY - I think this stood for Buffalo Evening News
KENS in San Antonio is for Evening News Station (I’m not positive about that)
Des Moines used to have KRNT radio, TV, and a civic auditorium. The R n T stood for “Register and Tribune”, the city’s newspapers back in the day. Later, the Tribune was combined with the Register.
Quincy, Illinois has KHQA, which unofficially stands for “Keokuk/Hannibal/Quincy Area”.
A few have used Roman numerals. WXIX was a Milwaukee TV station on channel 19, and KLVI in Beaumont, Texas was at 56 on the AM dial. (The late Big Bopper was a DJ at KLVI.)
Nashville has WVOL-AM, named for the Volunteer State of Tennessee. The station has primarily targeted the African-American community since before the name change in 1957, so I doubt (but can’t prove) that the name represents either the then-mostly-segregated University of Tennessee or the all-white AA baseball Nashville Vols.
St. Louis MO has KMOX radio, home of Cardinal Baseball. And Rush Limbaugh, I’m still sorry to say.
In L.A. we have:
KLAC (Los Angeles California)
KLOS
and, uh, KRTH (K-Earth) which does indeed broadcast from Earth.
There’s probably a million more in Spanish that I don’t recognize.
Slight hijacks:
There is KBLA, which is sadly not talk radio, but religious radio in Spanish.
From March 1 through October 31, 2016, L.A. had an AM station (KFWB) that broadcast Bollywood music, and I somehow never knew about it.
The NPR affiliate in West Lafayette, Indiana is WBAA, a nod to the fact sheep are involved in Purdue University’s teaching of agriculture and veterinary medicine.
Cleveland’s WEWS-TV (ABC affiliate) honors E. W. Scripps, founder of the station’s parent company.
Logically enough, WAKR is a radio station serving Akron, Ohio. There also used to be a WAKR-TV (ABC affiliate), but it changed its call letters to WAKC-TV in 1985, perhaps a nod to the fact Canton is part of the Akron market. (The station is now affiliated with Ion Television, and is known as WVPX-TV.)
Houston has KHOU.
There’s also KCMO in Kansas City, Missouri. 