I will preface this by saying I know very little of Doc Savage.
However, I read almost all the Destroyer books. Based on how Remo was presented there, I’d have to say he wins. He’s not trained to fight (although his battles with Nuihc are the stuff of legend); he’s trained to kill … quickly, efficiently, and with as little fuss as possible.
“I am created Shiva, the Destroyer. Death, the Shatterer of Worlds. I am the dead Night Tiger made whole by Sinanju. Who is this dog meat that comes before me?”
“I am created Shiva, the Destroyer. Death, the Shatterer of Worlds. I am the dead Night Tiger made whole by Sinanju. Who is this dog meat that comes before me?”
“Erk, ecch, who just sprayed me with cheesburger essense, arrgh, I’m sick, help me…”
I’m not familiar with Remo, but I do think Doc would be at a disadvantage without his vest of gadgets. Or the things he hides under false skin patches. Or in his hair. Or his hollow teeth.
Even though he was able to kill a polar bear and rip off a steak with his bare hands.
How about if we change the rules to allow only non-lethal combat? Doc seems to go out of his way to avoid killing folks most of the time. Would that be enough to give him the edge?