Princess Bride - keep either Prince Humperdink or Count Rugen as human. Rizzo as the other one? Or Animal.
Kermit as Westley, Piggy as Buttercup, Sweetums as Fezzick is a lock, Great Gonzo as Montoya. Pepe as Vizzini or Fozzy? Swedish Chef as the Priest, Bunsen as Miracle Max, maybe, but who for his wife? Or maybe Statler and Waldorf for that pair? I like Beaker for the Albino.