I can’t take it seriously. Buck Dharma is one of the greatest lead guitarists ever (IMO), and he’s not even listed. And B.B. King is #6?? He was O.K., but I wouldn’t put him in the top 20. Joni Mitchell and Joe Walsh should be much higher. I love The Ramones, but Johnny shouldn’t even be on the list. Same goes for Kurt Cobain and Lou Reed.
It’s just a list of 100 popular and influential popular American music guitarists. For what it is, it’s as reasonable as any other list, IMHO. My list might have Jimi on top, but probably not the rest of the top 10. But nothing strikes me as particularly egregious. OK, I may not agree with Frusciante being only one spot ahead of Cobain, or Johnny Marr being that much lower than The Edge, or Johnny Ramone (God bless him) being on this list at all, but, eh, it works fine for me.
Terry Kath from Chicago really deserves to be somewhere on that list. Also, I would rank Andrew Latimer of the band Camel as being roughly on the same level as David Gilmour, but he is probably too obscure for them to have even considered him.