I’m sure there’ll be quite a few of the old standbys, but I suspect this’ll at least as fertile ground as comics.
I’ll start things off with my undisputed favourite at the moment–it’s hard to think someone might displace her any time soon, but y’never know:
The Boss, from Metal Gear Solid 3. There’s just something about a strong woman. I don’t suppose she has what counts as ‘classic’ good looks, but I’ve never been much for those anyway…
Also from the MG games, Fortune and Vamp would have to be on my list–although the latter is a tiny bit creepy, and both, I think, have, um… issues. But they’re still wicked hawt.
I can’t believe this is your first choice. It’s mine too, in fact, I started a whole thread about this at some point. The Boss is definitely the sexiest Metal Gear woman ever. Try telling that to any other MG fans though. They prefer the stereotypically hot ones.
I figure someone has to say Lara Croft around this point. So yes.
Personal picks: Sora (aged a couple of years) and/or Riku from Kingdom Hearts 1 and 2; Mitsurugi and Raphael from Soul Caliber; Cloud, Vincent, and Sephiroth from Final Fantasy.
Jessica from Dragon Quest VIII - I’m not normally a breast man, but…oh my god, her bosom is hypnotic.
Yuffie from FFVII and Rikku from FFX - they’re…cute. So very cute. Rikku in X-2, not so much.
I have an unholy attraction to Tira from Soul Cal III. She’s hot, she’s scary, and…and…do I really need another reason? And she’s the only character in the game who looks good in both of base her outfits. Although Talim (who’s also a cutey, but not near as hot) doesn’t look too bad in either of hers.
And on the male side…
Sephie, of course (Kingdom Hearts version, please.) and Siegfried from Soul Cal are absolutely beautiful men.
For a second there I thought you were talking about Selphie who is like 10 in that game. Very cute, but not sexy. KH Sephiroth is one pretty man though…
Since I’m currently looking at her and none of the undoubtedly amazing ladies you’re suggesting, my vote will go to Alyx of Half-Life 2. Smart, brave, and I can tell she likes me. Or perhaps it’s my Big Gun she likes.