Probably with about as much success as with any other wild animal who is not afraid of you. Which means maybe; I have made friends with raccoons at my bird feeder but it’s not easy, and using food might be considered cheating.
The only one I know of for sure was the St. Louis Zoo, which years ago had several, then one more when we gave them our family pet (see below). All the zoo animals were deodorized, since the public would be at risk otherwise, not to mention the keepers.
I don’t put much credence into that. Only a vet or someone with a better knowledge of skunk anatomy can say for sure, but I don’t think there is anything about the legs that affects the spray glands and muscles. I think the scruffy-neck grabber would get a real eyeful. Maybe the pest control guy was trying to get you to try, snipe-hunt style, to pick up a skunk so he could be a good laugh at your expense?"
A Skunk Story
Onceuponatime, my uncle decided our family needed a skunk for a pet, so he set a live trap for one in the woods. I don’t know how he planned to limit the catch to just a skunk, but it worked, and we caught one. The local vet was called, he anesthetized the animal and removed the glands.
But a few days later, a neighborhood girl was playing with the skunk and it got away. Doubly bad, since not only were we out one (1) gland-less skunk, but the animal didn’t know it no longer had any defense.
But we just had to have a skunk. The trap was set again, one was caught again, and the vet came out again. But this time there was no charge.
That’s right, it was the same skunk! Stupid or lucky? Anyway, we took it home, named it Tinkerbell, and kept her in the basement where she held down the bug population and learned to eat out of our hands.
We had to remember to tell any workmen or meter readers who went into the basement, “Oh, by the way, there’s a skunk down there. But she won’t hurt you – just give her a cookie.”
A deodorized (gland-less) skunk has no smell, BTW.
The time came for us to take a long vacation, but kennels don’t board skunks and it would have been cruel to let her go into the woods. Luckily, we knew the head of the St. Louis Zoo, who accepted Tinkerbell, who had grown a bright white stripe and was much prettier than the other zoo animals whose stripes had turned yellow.
Tinkerbell lived at the zoo for years. Every summer, the kids would capture bugs in the schoolyard and the zookeeper would let us get behind the spectator bars so we could hand-feed live grasshoppers. Delectable to the skunks, and the kids would squeal with icky delight.