One of the big changes is that of fully active crossovers.
Typical passive speakers have crossover units made up from a network of inductors(coils of wire on formers) along with capacitors and perhaps some resistors.
They divide the signal into bands and direct these signals to the speaker elements that can cope with a particular range of frequencies.
The problem is that with passive crossover networks, you cannot get an ideal filtering effect, so that there is always a compromise, IIRC the best you can do is around 6dB per octave, and it means that you end up with a small amount of the wrong frequency signal reaching the wrong speaker element, they also use up power but in a frequency dependant manner.
Things have moved on greatly, signals are transmitted through cables or through optical links from the master unit, which does not have a power amplifier in it.
The digital stream is sent to the speaker, where it is seperated into high medium and low frequency bitstreams, each of which is converted to an analogue signal, which is amplified and is directed to the relevant speaker element.
The digital filtering allows very precise control over which band of frequencies is sent to which speaker element.
In addition to all this, the power supplies in many of these speakers are switch mode units, similar to the type in your computer, which allows for a far smaller unit, which has better current regulation, and increases the dynamic range.
This describes a fully active crossover, and is being employed by Meridian, Bang & Olufsen, Thomason among others.
Another advantage of the active crossover is that you can acoustically monitor the room and change the equalisation though the active network to compensate for any shortcomings.
I also think that Bang & Olufsen also go somewhat further than this, by using final drive amplifiers that are class D bias - effectively digital, which enables things to be even more compact, but this means that the speaker elements have to be constructed with this kind of drving amplifier in mind.
http://www.hometheaterhifi.com/volume_9_4/feature-article-active-speakers-12-2002.html
http://sound.westhost.com/biamp-vs-passive.htm
The other big change I can think of is the acoustic lens, which is a way of ensuring that the sound coming from the speaker goes straight to the listener and that ceiling and ground reflections are minimised, its effectively creating a horizontal beam of sound
http://www.bang-olufsen.com/web2/competences/competences.asp?section=competences&sub=sd&page=sD
It makes these speakers very predictable, every pair can be made within very much tighter limits than can passives.
These speakers are around £10k a pair, but they kick out 2500 Watts apiece, and even the audiophile publications seem to be highly impressed.
I’d expect that others will latch on to the technology.