In my Documentsa and Settings folder I have the following profiles (sub-directories):
I’m the only user on the machine and I’d like to get rid of any unnecessary profiles. When I go into User Accounts via the Control Panel, the only accounts I see are El Zagna (Computer Administrator) and Guest (Guest account is off).
So which of these accounts (profiles?) can I safely get rid of and how do I do it?
“All Users” and “Default User” are required. “All Users” contains information (registry, Start Menu, etc.) that is shared amongst all users of the computer, and holds some critical stuff. “Default User” is the profile that is copied when a new user is created, amongst other things.
All the others can probably be safely deleted, as far as the computer goes. I would look into each one before deleting, however, and make sure you don’t nuke any documents you want to keep.
And if by deleting anything you make something break or go missing, please keep in mind that this is free technical support and there are no guarantees. 
Getting a bit more technical, not sure it will help: The “Administrator.ELZANGA” and “Owner.DDTLMW11” profiles are there because a different “Administrator” and “Owner” (respectively) had already logged in beforehand. “ELZANGA” and “DDTLMW11” are either workstation names or domain names. The computer added the computer name or domain name after the account name to help keep the accounts separated.