I use both, because it’s worth the extra price to have less hassle at home, but at work I have to use what they give me.
On the PC I frequently use the Home and End keys to put the cursor at the left and right ends of the current line of text. That’s really handy during editing. I don’t know why that doesn’t have a single key counterpart on the Mac (and please tell me if I missed it!).
On the Mac it is normal good practice to work as a user who does not have system admin rights, and to switch user or log in as admin to mess with the system. This is nice because accidental damage is less likely. I think there’s a range of ways of dealing with it on the PC but they take initiative. It is also typical on the Mac to set up a user named Test or some such, and log in as that user if you want to try things you think might mess up the system, as any user can generally only mess up things in their own workspace.
I absolutely use Insert and Overwrite modes on the PC. Usually it’s in Insert mode, but for example when editing columns of numbers it can be much faster to use Overwrite.
On a PC the Delete and Backspace keys remove things in one direction or the other. On a Mac there’s the Backspace, and a Function-Backspace to do what the Del key does. I really do use the Del key on a PC often, whereas on the Mac my habit is more to position the cursor right of what I want to delete and the Backspace.
On the PC you have to deal with antivirus software, whereas on the Mac you don’t. This was a big deciding factor for me a decade ago when I switched at home.
On the Mac, after you have booted the system, if you use an application it remains open even when you save whatever file you created and close its window. The application code remains resident in memory. In the bar along the bottom (usually) of a Mac’s screen, this is indicated by a dot under the application’s icon. You have to close the application itself, with a right click on its icon or a Quit from the Apple menu, if you want the code to leave memory. On the PC, closing a window removes the application code from memory, and using an application for the second time since a boot takes as much time as using it the first time.
Macs do things with disk images. I’m not aware of a similar agent on PCs.
The default scroll directions are opposite. I go back and forth daily and every time I scroll it is a fresh journey of surprise and discovery to see which direction things move. Yes, you can change this. No, I never get around to it.
On the Mac, having multiple displays keeps screwing up, as they go dark or trade places or spontaneously rearrange themselves. Whereas, on the PC, exactly the same thing also keeps going wrong. I often wonder why this is so difficult.
Online vendors have been caught figuring out which kind of system shoppers are using, and showing higher prices to Mac users and lower prices to PC users.
These are all things I picked up on over the ten years I have been using both systems daily. I could have mistaken things and certainly some of these may have stopped being true without my noticing, so I would greatly appreciate anybody correcting whatever I got wrong!