The -caine suffix

I think I’ve gathered that the “-caine” suffix is applied to anaesthetics (e.g. novacaine, hydrocaine), typically associated with dentistry. However, what are the more specific conditions related to being a -caine?

“Cocaine” was the original “-caine” (as in Coca-ine). Suffixes for similar alkaloids just followed this pattern. Kinda like calling someone a “Chocoholic”.

I’ll look for a site.

cite.

I’ll look for a cite. Jeez. But maybe the cite will be a site.

(The key word there is “synthetic alkaloid anesthetic”)

The quick cite I found says the exact same thing:

http://www.bartleby.com/61/4/C0020400.html

So, “Novocaine”–Nova-caine–is the “New synthetic alkaloid anesthetic”.

“Lidocaine” is a bit more roundabout:

http://www.bartleby.com/61/50/L0155050.html

IIRC, older antipsychotics were members of the -caine family, the theory of their mechanism of action being in part that they anesthetized parts of the brain.

No, it will be a sight.

:smiley:

This is not a complete answer.

But cocaine, bupivicaine, marcaine, lidocaine etc. share the property of being local or regional anesthetics which don’t work well in acidic enviromenents (abcesses) as chemically they are amides (as opposed to esters).

I’m curious. Can you recall the name of any of these?

QtM, my error. Thanks for your question. I was actually thinking of the use of the “-zine” antipsychotics, which were also anaesthetics.

Novocaine and lidocaine are the same thing. As is Xylocaine.

What about Michaelcaine? Or Mutinycaine?

I don’t know much about them… Except that I am EXTREMELY allergic to them thanks to small tests after other people in my family showed slight problems with the -canes. If I was given a shot to numb my mouth I would probably die.

Or Quaichaucaine, which will use martial arts on your pain? :slight_smile: