Here’s the core of the issue:
You’re talking about a fictional TV show.
This thread isn’t about a fictional TV show. It’s about an idea espoused in the TV show.
In reality, regardless of what happens on your television, casually interfering in other races affairs, even those who have no potential for recourse, is a bad idea.
We’re going to assume that we have the capability for FTL travel, we’re not going to assume that we have replicators (magic make-stuff devices), because that’s not within the context of the thread. We don’t exist in Star Trek, so our discussion is one based in our reality, not theirs.
The best consequence, for humanity, of interference with a more primitive specie is economic drag for a decades, maybe centuries. The worst is alienation of a potential ally, even outright war with one a few generations down the line.
That doesn’t mean we should ignore them entirely. It means that we shouldn’t stumble blindly from system to system scream “Yo’ home dawg, have a goddamn hot pocket, they’re scalding hot on the edges and freezing inside. Yummmy!”
If we’re to “uplift” a civilization, it should be more along the lines of a single project, undertaken with the support and attention of an entire society. Something planned, carefully, and done slowly.
A lot of that depends on where in their society you meet them. If they’re not yet in their industrial revolution, introduction would be far different than if they’ve got their first extracelestial (whether they’re located on a moon or planet, who’s to say?) base.
It’d also be a lot different if their prevailing religious beliefs led them towards rabid xenophobia, or if they were even remotely similar.
Like before, how do you classify an individual? Each body, of course. By our standards. What of hive-insects? What of a race of intelligent collonials?
Applying our morality to the universe is like a bicycle mechanic applying his expertise to relativistic effects on an interstellar mission. It’s simply not applicable.