No, not MILF (Mothers I’d Like to** F*****).
VILF.
Villainesses I’d like to F***!
The Bad Girls, from Movies, TV, Comics, whatever, who have a special…appeal! 
The Baroness , Chief Intel Officer of Cobra springs to…mind.
Any Villainesses get the SDMB’s attention?
The Baroness was exactly who I was going to mention.
Sizzzzzzle!
Hedy Carlson from Single White Female
Can we do Villains, too?
Shego–and her inspiration, Viper/Madame Hydra.
(As Hawkeye said, there’s something about green women.)
Lady Sabine DeWinter as portrayed by Rebecca De Mornay
Why not?
Evil is Equal Opportunity.
Intendant Kira from the Mirror, Mirror universe in Deep Space 9
Evil Kes as possessed by the evil bad guy, all dressed up in black leather in Voyager
Six from Battlestar Galactica
Famke Janssen as Xenia Onatopp. And hey, speaking of X-Men, I’ll bet Mystique would make one hell of a wild ride in the sack.
I came in to mention various females from my old Marvel card collecting days.
God I suck.
I’m…assuming that, for the situation the OP’s thinking of, whatever villainess isn’t just going to murder me afterwards (or during)? Cause…y’know…that’d just ruin the whole experience for me in advance. But maybe that’s just me.
But yeah, Baroness, Mystique, Shego…they’re the ones who come to mind for me, too, but I should probably still add someone else.
Hmmm…
…evil Gadget from Rescue Rangers? Not count?
The Lucy Liu character in Payback, if you please.
The trouble with villainesses is that you have to liquidate them so early into a love affair that you really end up having a series of meaningless flings, and that takes a villains mind off the business at hand. Nonetheless, I’ve always been fond of Alotta Fagina, who was feathured in an excellent 1997 spy documentary.
I can’t find anything on imdb, but I distinctly remember one of the Power Ranger clones that was playing in Japan around '96 or '97, the woman playing the queen of the monsters was either currently working in or had just left hardcore porn (one of the female rangers had also just released a book of nude photos, so overall it was a fun show). I also recall her costumes on the show weren’t much less revealing than her film outfits. So there’s a VILF that I’ve seen F’ing.
How about sons of villains who aren’t really villains themselves but might be someday? Cause I’d be all over Scott Evil.
The beauty of the VILF concept is the lack of potential for a long term relationship, but of course self preservation can be a problem. My choice is Lilah Morgan from Angel but I may think of others later.
All of mine are from video games.
Villainess - Rosso the Crimson from Final Fantasy 7: Dirge of Cerberus. I think I just like russian accents.
Villain - Seifer Almasy from Final Fantasy 8.
I’m such a fangirl.
~Tasha
Doctor Girlfriend, even if she does have a baboon’s uterus … .
Lightning Lady, from Evil Inc has possibilities.
At least 2.
The Boss from Metal Gear Solid 3. All the other villainesses in video games seem too stereotypically “hot” for me, but this character actually seemed like a rugged, take-no-shit woman who also had a haunting sense of loneliness about her - a really well-developed character all around, with a great voice also.
