What happens if you mix uppers and downers?

[QUOTE=jjimm]
In the past have combined alcohol with stimulants of varieties I shall not mention here. The result was that I went from being a sleepy drunk person who slurred their words into a drunk person who was wide awake and talking gibberish with perfect diction.
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Ditto for me, except I wasn’t talking gibberish. I had (note the past tense - I haven’t used it in a long time, and never was a frequent user) cocaine, Xanax (which was prescribed to me), and copious amounts of alcohol.

It was one of the most enjoyable nights of my life, but as others have noted, it is dangerous, and I am most certainly not recommending it.

[QUOTE=Priceguy]
Is there any particular effect associated with taking stimulants and depressants at the same time, say amphetamine and opium?
[/QUOTE]

Either way, blood flows.

(Sorry; Who fan checking in)

[QUOTE=Shagnasty]
They usually don’t directly cancel each other out so you can get all kinds of crappy effects
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So you don’t just walk around thinking “Meh”?

[QUOTE=Kevbo]
Actifed, an OTC hayfever remedy is a mix of an antihistamine, (which causes drowseness) and pseudoephederine, which is a decongestant, and also a stimulant. The idea was to have an allergy pill that didn’t make you drowsy.

Stuff works for me, with little noticeable side effects initially, but tends to make me grumpy if I take it for more than a day or two straight.
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In college back in the 70’s, our infirmary used to hand this stuff out if we had a nasty head cold. I truly thought it was the cure for the common cold – for me, it just completely knocked me out for so long that when I actually woke up again, I really DID feel better. I’ve always wondered what strength they used to give us, becuse the OTC stuff never had quite that same effect!

In any case, for me, drowsy won out over stimulant every time, but then again, I’m very weird.