What happens if you mix uppers and downers?

Is there any particular effect associated with taking stimulants and depressants at the same time, say amphetamine and opium?

You go sideways.

You have FUN!!

:smiley:

You can die.

Next question!

Anxiety, heart palpatations, blurred vision, memory loss, extreme mood swings, inabilty to concentrate, feelings of overwhelming dread, hallucinations, tactile sensations, coma, death.

IANAD, anecdotal evidence

I once asked a similiar question.

Whatever question can be asked, somewhere on the Internet there’s a forum discussing it.

The biggest problem seems to be the sudden, unpredictable heart failure.

You go for a ride on a Pogo stick!

          :rolleyes:

They usually don’t directly cancel each other out so you can get all kinds of crappy effects. Alcohol is a potent CNS depressant and most people know what it feels like to get drunk. Throw in some stimulants and you could be a drunk with a racing heart, panic reaction, inability to sleep, and weird psychological effects. Best case would be that you might be more alert but you still drunk.

Larry Niven once defined Irish Coffee this way. Coffee to lift you up and whiskey to bring you down.

Mild compared to pills, though, I’d wager.

That’s pretty much the idea behind Red Bull and Vodka too. Although, like you, I’m sure it can’t compare to taking amphetamines.

The problem, as I understand it, is that some drugs potentiate, or make stronger the effects of, other drugs. So your upper may make you downer even more downer-like, to the point where your brain forgets to tell your lungs to breathe. Or your downer may mask the effect of your upper, making you think you’re not as upper as you are, when in fact your heart is about to burst.

Generally, not good to mix your madness. Pick a frame of mind and stick with it.

With or without benzodiazepines?

Oh thanks-now I’m craving an Irish coffee. Dammit.

You’re a little slip of a girl, Guin. Betcha it knocks you right out.

Frankly, that’s good advice for most situations.

In the past have combined alcohol with stimulants of varieties I shall not mention here. The result was that I went from being a sleepy drunk person who slurred their words into a drunk person who was wide awake and talking gibberish with perfect diction.

I also once combined a hallucinogenic with a stimulant, which made me into a reflective person who wanted to dance like a maniac, but was too aware of everyone looking at them to enjoy it.

Those reasons, and the chance of dropping down dead, means the above are not recommended.

On the extreme side, It’s called ‘speedballing’ and it kills celebrities.

According to my dentist, mixing of uppers and downers results in severe malocclusion. :smiley:

Actifed, an OTC hayfever remedy is a mix of an antihistamine, (which causes drowseness) and pseudoephederine, which is a decongestant, and also a stimulant. The idea was to have an allergy pill that didn’t make you drowsy.

Stuff works for me, with little noticeable side effects initially, but tends to make me grumpy if I take it for more than a day or two straight.

I thought the idea was that Triprolidine is an antihistamine and pseudoephedrine is a decongestant, so together they’re more likely to clear out your snot.

Actifed carries all the warnings of both a depressant and a stimulant, because it’s impossible to know how the combo will affect any individual. For some people, it’s less likely to cause drowsiness, but all the drowsiness warnings are still there. cite