Not to mention the various Queen Bees, and Lana Lang’s stint as Insect Queen.
Cicada man- No comic character I know of, but the idea of a half man half cicada who pops up every 17 years was the idea behind the movie The Beast Within. It’s bad but I’ve seen much worse.
Platypus Man- Was the name of a short lived sitcom on either UPN or the WB. After learning that the platypus was fat, nocturnal, had stubby legs etc a comedian whose name escapes me at the moment decided it was his totem animal and called himself Platypus Man. This did not involve a costume or fighting crime.
So what’s the score now? Doc Cathode: 20-something Rest of the Dope: Two-and-a-half? 
First, it’s not a contest.
Second, Fenris and CMKeller know tons more about comics than I do.
As well as a villain actually named Iguana.
I’ve not seen a comic about FerretMan, but I do know it was used as a rip-off of Batman in Kim Possible. He was the Fearless Ferret, and he was played by Adam West.
Batman-themed, but Asif Mandvi interviews a man bitten by a bigoted spider (from around 2:40 on to catch the quote).
I think it’d be interesting if you gave him real spider powers. He could drain villains of their blood and shoot spider webs from his ass. 
I remember hearing about that show – it was part of UPN’s first season. (Side note: UPN’s first season had 100% turnover to the second season AND one show that survived to the second season. The quirk is due to one show being cancelled mid-season.)
Nu. 20 to 4.
Miguel O’Hara, Spiderman 2099, commented on this. ‘At least I’m not perfectly mimicking a spider. Then, I’d be shooting webs out my butt.’
One of the Mystery Men (I forget which one) mentions the time they fought Spider Boy- who liked to climb walls and eat flies.
There was also the first Tarantula, who tried to get spider based powers like Spiderman and turned himself into a spidery semi-humanoid who eventually degenerated into a full giant spider. Who, yes, shot webbing out of his rear when he reached that point, and when he looked back to find where the webbing was coming from saw what he’d become and jumped to his death.
Would he become humanman if he was bitten by a radioactive human?
Maybe, or he could become Hanuman after being bitten by a radioactive monkey god.