What is the difference in Pain Relievers

General Questions
#1

I am refering to over the counter types.

I know there are two categories

NSAIDS (Non Steriodal Anti Inflamitory Drugs)

ASPRIN, NAPROXEN, IBRUPROFEN And KETOPROFEN.

{BAYER, ALEVE, ADVIL, & ORUDIS - are example of brand names of the above)

And Non NSAIDS

ACETAMINOPHEN - {TYLENOL}

I know Tylenol (I will use brand names it is easier to spell but I am refering to generics as well) don’t relieve inflammation and are gentler

But I have found Ibruprofen and Asprin work about the same for me yet Orudis and Aleve do almost nothing. (Yet cost more)

More pointedly what is the difference between the NSAIDS?

#2

They are all NSAIDS. Some have worse side effects, like aspirin and intestinal problems from long term use. The new cyclooxygenase II inhibitors, like the one Monsanto/Searle put out(name?), are more specific. Most NSAIDS inhibit Cox I and Cox II .It’s prescribed for arthritis now, but may get wider use. Other companies are also developing this new generation of NSAIDS.